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Article

Effects of childhood trauma experience and BDNF Val66Met polymorphism on brain plasticity relate to emotion regulation.

Behavioural brain research - 1 Feb 2021

Tian Tian, Li Jia, Zhang Guiling, Wang Jian, Liu Dong, Wan Changhua, Fang Jicheng, Wu Di, Zhou Yiran, Zhu Wenzhen

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism may modulate the link between childhood trauma experience and psychopathology by altering trophic signaling on neuroplasticity. However, few multimodal magnetic resonance imaging (MRI) researches have investigated this gene-environment interaction on both structural and functional plasticity, thereby advancing knowledge about the etiology, prevention,...

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Identifiers

PMID: 33053385
DOI: 10.1016/j.bbr.2020.112949

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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