Article
Differential Genetic Effects on Statin-Induced Changes Across Low-Density Lipoprotein-Related Measures.
Circulation. Cardiovascular genetics - 1 Oct 2015
Chu Audrey Y, Giulianini Franco, Barratt Bryan J, Ding Bo, Nyberg Fredrik, Mora Samia, Ridker Paul M, Chasman Daniel I
Abstract excerpt
BACKGROUND: Statin therapy influences not only low-density lipoprotein (LDL) cholesterol levels but also LDL-related biomarkers, including non-high-density lipoprotein cholesterol (non-HDL-C), apolipoprotein B, total number of LDL particles, and mean LDL particle size. Recent studies have identified many genetic loci influencing circulating lipid levels and statin-induced LDL cholesterol reduction. However, it is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
