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Article

Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.

Circulation. Cardiovascular genetics - 1 Dec 2008

Voora Deepak, Shah Svati H, Reed Carol R, Zhai Jun, Crosslin David R, Messer Chad, Salisbury Benjamin A, Ginsburg Geoffrey S

Abstract excerpt

BACKGROUND: There is interindividual variation in low-density lipoprotein cholesterol (LDLc) lowering by statins and limited study into the genetic associations of the dose dependant LDLc lowering by statins. METHODS AND RESULTS: Five hundred nine patients with hyperlipidemia were randomly assign...

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Source

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Identifiers

PMID: 20031551
DOI: 10.1161/CIRCGENETICS.108.795013
PMCID: PMC2995295

Genes

ABCA1
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20031551-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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