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Article

Polymorphisms and phenotypic analysis of cytochrome P450 3A4 in the Uygur population in northwest China.

International journal of clinical and experimental pathology - 1 Jan 2015

Jin Tianbo, Yang Hua, Zhang Jiayi, Yunus Zulfiya, Sun Qiang, Geng Tingting, Chen Chao, Yang Jie

Abstract excerpt

PURPOSE: Genetic polymorphisms in CYP3A4 can change its activity to a certain degree, thus leading to differences among different populations in drug efficacy or adverse drug reactions. METHODS: The study was intended to validate the genetic polymorphisms in CYP3A4 in Uygur Chinese population, we sequenced and screened for genetic variants including 5'UTR, promoters, exons, introns, and 3'UTR region of the whole...

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Identifiers

PMID: 26261601
PMCID: PMC4525935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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