Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of human UGT1A3: functional characterization and frequency distribution in a Chinese Han population.

Drug metabolism and disposition: the biological fate of chemicals - 1 Sept 2006

Chen Yakun, Chen Shuqing, Li Xin, Wang Xiewei, Zeng Su

Abstract excerpt

UDP-glucuronosyltransferase 1A3 (UGT1A3) contributes to glucuronidation of many important endogenous compounds and xenobiotics, including some flavonoids. Recently, a total of six single nucleotide polymorphisms (SNPs) have been identified in the human UGT1A3 gene. Among them, four SNPs (A17G, Q6R; T31C, W11R; C133T, R45W; and T140C, V47A) cause amino acid substitutions. Variants caused by these SNPs showed an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glucuronides

Share to Glucuronosyltransferase

Share to Kinetics

Share to Polymorphism, Single Nucleotide

Share to Quercetin

Share to Recombinant Proteins

Source

Identifiers

PMID: 16738032
DOI: 10.1124/dmd.106.009761

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of human UGT1A3: functional characterization and frequency distribution in a Chinese Han population.PMID 16738032Read ↗

Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity.Semantic proximity Read ↗

Allele and genotype frequencies of CYP3A4, CYP3A5, CYP3A7, and GSTP1 gene polymorphisms among mainland Tibetan, Mongolian, Uyghur, and Han Chinese populations.Semantic proximity Read ↗

A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3.Semantic proximity Read ↗

Genetic polymorphisms of the drug-metabolizing enzyme cytochrome P450 3A5 in a Uyghur Chinese population.Semantic proximity Read ↗

UGT3A: novel UDP-glycosyltransferases of the UGT superfamily.Semantic proximity Read ↗

UGT pharmacogenomicsSemantic proximity Read ↗

Polymorphisms and phenotypic analysis of cytochrome P450 3A4 in the Uygur population in northwest China.Semantic proximity Read ↗

Comprehensive variant screening of the UGT gene family.Semantic proximity Read ↗

UGT pharmacogenomics: implications for cancer risk and cancer therapeutics.Semantic proximity Read ↗

Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1, UGT1A8*2 and UGT1A8*3.Semantic proximity Read ↗

Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.Semantic proximity Read ↗

Genetics of the Variable Expression of CYP3A in HumansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.