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Article

Genetic insight into cytochrome P450 in Chinese from the Chinese Millionome Database.

Basic & clinical pharmacology & toxicology - 1 Apr 2020

Qi Guangzhao, Han Chao, Sun Ya, Zhou Yubing

Abstract excerpt

Genetic variations of cytochrome P450 (CYP) influence the inter-individual differences in drug response. Here, we collected 8682 variants of 57 CYP genes and cytochrome P450 oxidoreductase (POR) from a large-scale sequencing project in Chinese, Chinese Millionome Database (CMDB). In addition, 52 294 variants from the Genome Aggregation Database (gnomAD) had been simultaneously identified and analysed. Rare...

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PMID: 31661191
DOI: 10.1111/bcpt.13356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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