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Article

Genetic analysis of drug metabolizing phase-I enzymes CYP3A4 in Tibetan populations.

Journal of genetics - 1 Jun 2017

Liu Lijun, Chang Yu, Du Shuli, Shi Xugang, Yang Hua, Kang Longli, Jin Tianbo, Yuan Dongya, He Yongjun

Abstract excerpt

The enzymatic activity of CYP3A4 results in broad interindividual variability in response to certain pharmacotherapies. The present study aimed to screen Tibetan volunteers for CYP3A4 genetic polymorphisms. Previous research has focussed on Han Chinese patients, while little is known about the genetic variation of CYP3A4 in the Tibetan populations. Here, we adopted DNA sequencing to investigate the promoter,...

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PMID: 28674221
DOI: 10.1007/s12041-017-0757-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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