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Systematic screening for polymorphisms in the CYP3A4 gene in the Chinese population.

Pharmacogenomics - 1 Sept 2006

Du Jing, Xing Qinghe, Xu Lingyun, Xu Mingsheng, Shu Anli, Shi Yongyong, Yu Lan, Zhang Aiping, Wang Lei, Wang Hongsheng, Li Xingwang, Feng Guoyin, He Lin

Abstract excerpt

OBJECTIVES: Cytochrome P450 3A4 (CYP3A4) is a major CYP enzyme in the liver and intestine. It is involved in the metabolism of over 50% of all drugs currently in use. The present study was designed to determine the genetic basis of CYP3A4 variability. METHODS: Single nucleotide polymorphism (SNP) analysis of the CYP3A4 gene was performed on 60 healthy Chinese subjects consisting of 20 Han, 30 She and ten Dong...

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Identifiers

PMID: 16981844
DOI: 10.2217/14622416.7.6.831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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