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Article

Effect of shRNA targeted against RhoA on proliferation and migration of human colonic cancer cells.

International journal of clinical and experimental pathology - 1 Jan 2015

Wang Man, Wang Xiu-Jie, Liu Bing-Rong

Abstract excerpt

OBJECTIVE: To study the effects of RhoA siRNA on the malignant phenotypes of human colorectal cancer cell line LoVo. METHODS: The siRNA expression vector pGPU6/GFP/Neo-shRNA-RhoA targeting the mRNA of RhoA and vector pGPU6/GFP/Neo-NC (as a control) were constructed, and then transfected into LoVo cells. The expression of Survivin was detected by real-time fluorescent quantitative polymerase chain reaction and...

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Share to Colonic Neoplasms
Share to Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inhibitor of Apoptosis Proteins

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Share to rhoA GTP-Binding Protein

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Source

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Identifiers

PMID: 26261596
PMCID: PMC4525930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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