Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2004

Liu Na, Bi Feng, Pan Yanglin, Sun Lijun, Xue Yan, Shi Yongquan, Yao Xuebiao, Zheng Yi, Fan Daiming

Abstract excerpt

PURPOSE: The small GTPase RhoA has been implicated in the regulation of cell morphology, motility, and transformation, but the role of RhoA protein in the carcinogenesis of gastric cancer remains unclear. In the present study, we have analyzed the expression status of the RhoA protein in human ga...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Agar
Share to Antibiotics, Antineoplastic
Share to Antimetabolites, Antineoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Doxorubicin

Share to rhoA GTP-Binding Protein

Share to Tetrazolium Salts

Share to Thiazoles

Share to Wound Healing

Source

Identifiers

PMID: 15448013
DOI: 10.1158/1078-0432.CCR-04-0242

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15448013-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity.PMID 15448013Read ↗

A distinct role of RhoB in gastric cancer suppressionSemantic proximity Read ↗

RhoC is essential for the metastasis of gastric cancerSemantic proximity Read ↗

Aberrant alternative splicing of RHOA is associated with loss of its expression and activity in diffuse-type gastric carcinoma cells.Semantic proximity Read ↗

Knockdown of RhoGDI2 represses human gastric cancer cell proliferation, invasion and drug resistance via the Rac1/Pak1/LIMK1 pathwaySemantic proximity Read ↗

Identification of "regulation of RhoA activity panel" as a prognostic and predictive biomarker for gastric cancer.Semantic proximity Read ↗

Effect of shRNA targeted against RhoA on proliferation and migration of human colonic cancer cells.Semantic proximity Read ↗

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma.Semantic proximity Read ↗

INHBA gene silencing inhibits gastric cancer cell migration and invasion by impeding activation of the TGF‐β signaling pathwaySemantic proximity Read ↗

The involvement of RhoA and Wnt-5a in the tumorigenesis and progression of ovarian epithelial carcinoma.Semantic proximity Read ↗

Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer CellsSemantic proximity Read ↗

RHOA mutation in diffuse-type gastric cancer: a comparative clinicopathology analysis of 87 cases.Semantic proximity Read ↗

RHOA drivers take alternate routes in gastric cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.