Article
Overcoming Therapy Resistance in Colorectal Cancer: Targeting Rac1 Signaling Pathway as a Potential Therapeutic Approach
2024-08-27
Abstract excerpt
Colorectal cancer (CRC) is the third most commonly diagnosed type of cancer worldwide and is responsible for numerous deaths. 5-fluorouracil (5-FU) is an effective chemotherapy drug commonly used in the treatment of CRC, either as monotherapy or in combination with other drugs. However, half of CRC cases are resistant to 5-FU-based therapies. To contribute to the understanding the mechanisms underlying CRC resista...
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Identifiers and source
- Literature Corpus work
- d4b85c03-f05a-5095-ab12-fb977c5afa0a
- DOI
- 10.20944/preprints202408.1939.v1
