Article
RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis
15 Jul 2011
Abstract excerpt
RhoGTPases are key signaling molecules regulating main cellular functions such as migration, proliferation, survival, and gene expression through interactions with various effectors. Within the RhoA-related subclass, RhoA and RhoC contribute to several steps of tumor growth, and the regulation of their expression affects cancer progression. Our aim is to investigate their respective contributions to the...