Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The involvement of RhoA and Wnt-5a in the tumorigenesis and progression of ovarian epithelial carcinoma.

International journal of molecular sciences - 12 Dec 2013

Chen Shuo, Wang Jun, Gou Wen-Feng, Xiu Ying-Ling, Zheng Hua-Chuan, Zong Zhi-Hong, Takano Yasuo, Zhao Yang

Abstract excerpt

BACKGROUND: Ras homolog gene family member A (RhoA) is involved in Wnt-5a-induced migration of gastric and breast cancer cells. We investigated the roles of RhoA and Wnt-5a in ovarian carcinoma. METHODS: RhoA and Wnt-5a mRNA and protein expression in normal fallopian tube epithelium, benign tumors, primary ovarian carcinomas, and metastatic omentum were quantified. RhoA or Wnt-5a was knocked down in OVCAR3...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogenesis
Share to Carcinoma, Ovarian Epithelial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to G1 Phase Cell Cycle Checkpoints

Share to Neoplasms, Glandular and Epithelial

Share to rhoA GTP-Binding Protein

Share to RNA, Small Interfering

Share to Wnt-5a Protein

Share to Wnt Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24351810
DOI: 10.3390/ijms141224187
PMCID: PMC3876104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The involvement of RhoA and Wnt-5a in the tumorigenesis and progression of ovarian epithelial carcinoma.PMID 24351810Read ↗

RhoC is a major target of microRNA-93-5P in epithelial ovarian carcinoma tumorigenesis and progressionSemantic proximity Read ↗

Rho GTPase signaling in the development of colorectal cancerSemantic proximity Read ↗

RHOJ Induces Epithelial-to-Mesenchymal Transition by IL-6/STAT3 to Promote Invasion and Metastasis in Gastric CancerSemantic proximity Read ↗

Rho proteins and cancer.Semantic proximity Read ↗

RhoB expression associated with chemotherapy response and prognosis in colorectal cancerSemantic proximity Read ↗

RhoA/C inhibits proliferation by inducing the synthesis of GPRC5A.Semantic proximity Read ↗

RhoC is essential for the metastasis of gastric cancerSemantic proximity Read ↗

GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathwaySemantic proximity Read ↗

Fixing the GAP: The role of RhoGAPs in cancerSemantic proximity Read ↗

Targeting Rho GTPase Signaling Networks in CancerSemantic proximity Read ↗

A distinct role of RhoB in gastric cancer suppressionSemantic proximity Read ↗

Comprehensive analysis on the whole Rho‐GAP family reveals that ARHGAP4 suppresses EMT in epithelial cells under negative regulation by Septin9Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.