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Article

Rho GTPase signaling in the development of colorectal cancer

3 Apr 2012

Abstract excerpt

The involvement of Rho GTPases in major aspects of cancer development, such as cell proliferation, apoptosis, cell polarity, adhesion, migration, and invasion, have recently been attracting increasing attention. In this review, we have summarized the current findings in the literature, and we discuss the participation of the Rho GTPase members RhoA, Rac1, and Cdc42 in the development of colorectal cancer, the...

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PMID: 22467564
DOI: 10.1002/jcb.24153

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