Article

Natural compound rhein suppresses colorectal cancer cells growth through mTOR/p70S6 kinase pathway in vitro and in vivo

2020-07-14

Abstract excerpt

<h4>Background: </h4> Rhein is a natural agent isolated from the traditional Chinese medicine rhubarb, which has been used as a medicine in China since ancient times. Although rhein was found to have significant anticancer effects in different cancer models, the effect and the underlying mechanisms of action of rhein in colorectal cancer (CRC) remain unclear. The mTOR/p70S6 kinase (p70S6K) pathway has been demonst...

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Literature Corpus work: a0b9cb6b-0fa0-5dd0-9775-54bea4535248
DOI: 10.21203/rs.3.rs-41306/v1

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