Article
Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancer
1 Jan 2020
Abstract excerpt
Colorectal cancer (CRC) is the second leading cause of death globally. Integrin 1 (ITGA1) belongs to integrin family and involves in regulating cell adhesion, invasion, proliferation and tumorigenicity, its expression is up-regulated in various cancers, including CRC. However, the molecular understanding and clinical relevance of ITGA1 in the development and progression of CRC remain unclear. In the present...
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