Identification of IDUA and WNT16 Phosphorylation-Related Non-Synonymous Polymorphisms for Bone Mineral Density in Meta-Analyses of Genome-Wide Association Studies.

doi:10.1002/jbmr.2687

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Article

Identification of IDUA and WNT16 Phosphorylation-Related Non-Synonymous Polymorphisms for Bone Mineral Density in Meta-Analyses of Genome-Wide Association Studies.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Feb 2016

Niu Tianhua, Liu Ning, Yu Xun, Zhao Ming, Choi Hyung Jin, Leo Paul J, Brown Matthew A, Zhang Lei, Pei Yu-Fang, Shen Hui, He Hao, Fu Xiaoying, Lu Shan, Chen Xiang-Ding, Tan Li-Jun, Yang Tie-Lin, Guo Yan, Cho Nam H, Shen Jie, Guo Yan-Fang, Nicholson Geoffrey C, Prince Richard L, Eisman John A, Jones Graeme, Sambrook Philip N, Tian Qing, Zhu Xue-Zhen, Papasian Christopher J, Duncan Emma L, Uitterlinden André G, Shin Chan Soo, Xiang Shuanglin, Deng Hong-Wen

Abstract excerpt

Protein phosphorylation regulates a wide variety of cellular processes. Thus, we hypothesize that single-nucleotide polymorphisms (SNPs) that may modulate protein phosphorylation could affect osteoporosis risk. Based on a previous conventional genome-wide association (GWA) study, we conducted a three-stage meta-analysis targeting phosphorylation-related SNPs (phosSNPs) for femoral neck (FN)-bone mineral density...

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Identifiers

PMID: 26256109
DOI: 10.1002/jbmr.2687
PMCID: PMC5362379

Genes

IDUA
WNT16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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