A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.

doi:10.1038/ng.612

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Article

A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.

Nature genetics - 1 Aug 2010

Uno Satoko, Zembutsu Hitoshi, Hirasawa Akira, Takahashi Atsushi, Kubo Michiaki, Akahane Tomoko, Aoki Daisuke, Kamatani Naoyuki, Hirata Koichi, Nakamura Yusuke

Abstract excerpt

Although the pathogenesis of endometriosis is not well understood, genetic factors have been considered to have critical roles in its etiology. Through a genome-wide association study and a replication study using a total of 1,907 Japanese individuals with endometriosis (cases) and 5,292 controls, we identified a significant association of endometriosis with rs10965235 (P = 5.57 x 10(-12), odds ratio = 1.44),...

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PMID: 20601957
DOI: 10.1038/ng.612

Genes

WNT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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