Article
Gene-based association analysis identified novel genes associated with bone mineral density.
PloS one - 1 Jan 2015
Mo Xing-Bo, Lu Xin, Zhang Yong-Hong, Zhang Zeng-Li, Deng Fei-Yan, Lei Shu-Feng
Abstract excerpt
Genetic factors contribute to the variation of bone mineral density (BMD), which is a major risk factor of osteoporosis. The aim of this study was to identify more "novel" genes for BMD. Based on the publicly available SNP-based P values, we performed an initial gene-based analysis in a total of 32,961 individuals. Furthermore, we performed differential expression, pathway and protein-protein interaction analyses...
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