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Identification of mutations conferring streptomycin resistance in multidrug-resistant tuberculosis of China.

Diagnostic microbiology and infectious disease - 1 Oct 2015

Zhao Li-Li, Liu Hai-Can, Sun Qing, Xiao Tong-Yang, Zhao Xiu-Qin, Li Gui-Lian, Zeng Chun-Yan, Wan Kang-Lin

Abstract excerpt

We investigated the spectrum and frequency of mutations in rpsL, rrs, and gidB among 140 multidrug-resistant tuberculosis (MDR-TB) clinical isolates from China. The association between mutations and different genotypes was also analyzed. Our data revealed that 65.7% of MDR-TB were resistant to streptomycin (STR), and 90.2% of STR-resistant isolates were Beijing strains. STR resistance was correlated with Beijing...

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PMID: 26254141
DOI: 10.1016/j.diagmicrobio.2015.06.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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