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Characterization of mutations conferring streptomycin resistance to multidrug-resistant Mycobacterium tuberculosis isolates from Myanmar.

Tuberculosis (Edinburgh, Scotland) - 1 Jul 2018

Thida Oo Nan Aye, San Lai Lai, Thapa Jeewan, Aye Khin Saw, Aung Wah Wah, Nakajima Chie, Suzuki Yasuhiko

Abstract excerpt

Numerous studies report that mutations of rpsL (encoding the S12 protein), rrs (encoding 16S rRNA) and gidB (encoding rRNA methyltransferase) are responsible for conferring resistance to streptomycin (STR), which is usually used in both multidrug-resistant tuberculosis (MDR-TB) treatments and re-treatments in Myanmar. The aim of this study was to explore the variation and frequency of mutations in rpsL, rrs and...

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Identifiers

PMID: 30029920
DOI: 10.1016/j.tube.2018.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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