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Genomic Analysis Identifies Mutations Concerning Drug-Resistance and Beijing Genotype in Multidrug-Resistant Mycobacterium tuberculosis Isolated From China

15 Jul 2020

Abstract excerpt

Development of modern genomics provides us an effective method to understand the molecular mechanism of drug resistance and diagnose drug-resistant Mycobacterium tuberculosis. In this study, mutations in 18 genes or intergenic regions acquired by whole-genome sequencing (WGS) of 183 clinical M. tuberculosis strains including 137 multidrug resistant and 46 pan-susceptible isolates from China were identified and...

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PMID: 32760357
DOI: 10.3389/fmicb.2020.01444

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