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Mutations in rrs, rpsL and gidB in streptomycin-resistant Mycobacterium tuberculosis isolates from Thailand.

Journal of global antimicrobial resistance - 1 Mar 2016

Smittipat Nat, Juthayothin Tada, Billamas Pamaree, Jaitrong Sarinya, Rukseree Kamolchanok, Dokladda Kanchana, Chaiyasirinroje Boonchai, Disratthakit Areeya, Chaiprasert Angkana, Mahasirimongkol Surakameth, Yanai Hideki, Yamada Norio, Tokunaga Katsushi, Palittapongarnpim Prasit

Abstract excerpt

The objectives of this study were to characterise mutations in rrs, rpsL and gidB genes in Mycobacterium tuberculosis isolates from Thailand and to examine possible associations between mutations and strain genotypes. In total, 110 streptomycin (STR)-resistant M. tuberculosis isolates and 51 STR-susceptible isolates obtained from a sample collection in Thailand during 1999-2011 were sequenced for mutation...

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PMID: 27436385
DOI: 10.1016/j.jgar.2015.11.009

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