Article
Rapid molecular screening for multidrug-resistant tuberculosis in a resource-limited region of China.
Tropical medicine & international health : TM & IH - 1 Oct 2014
Zhang Dan, Liu Beizhong, Wang Yufeng, Pang Yu
Abstract excerpt
OBJECTIVE: To investigate the molecular characteristics of MDR and XDR strains circulating in Chongqing, China. METHODS: The drug target genes conferring for rifampicin (RIF), isoniazid (INH), ethambutol (EMB), ofloxacin (OFLX) and kanamycin (KAN) resistance were screened by DNA sequencing to determine the mutation frequencies in this area. RESULTS: Drug susceptibility of 208 MDR isolates revealed that 132...
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