Article
Frequency of rrs and rpsL mutations in streptomycin-resistant Mycobacterium tuberculosis isolates from Iranian patients.
Journal of global antimicrobial resistance - 1 Jun 2017
Khosravi Azar Dokht, Etemad Nayereh, Hashemzadeh Mohammad, Khandan Dezfuli Solmaz, Goodarzi Hamed
Abstract excerpt
OBJECTIVES: Streptomycin (SM) is one of the most effective drugs for the treatment of multidrug-resistant (MDR) tuberculosis. However, resistance to SM is increasingly reported, mainly due to mutations in the rpsL and rrs genes. This study was designed with the aim of determining the nature of SM resistance and the type and frequency of rpsL and rrs mutations among SM-resistant Mycobacterium tuberculosis (MTB)...
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