Article
Phenotypic and Genotypic Characterization of Streptomycin-Resistant Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jul 2020
Islam Md Mahmudul, Tan Yaoju, Hameed H M Adnan, Chhotaray Chiranjibi, Liu Zhiyong, Liu Yang, Lu Zhili, Wang Shuai, Cai Xiaoyin, Gao Yamin, Cai Xingshan, Guo Lingmin, Li Xinjie, Tan Shouyong, Yew Wing Wai, Zhong Nanshan, Liu Jianxiong, Zhang Tianyu
Abstract excerpt
Streptomycin (STR) is the first antibiotic used in the treatment of tuberculosis (TB) and the earliest antituberculosis drug with acquired resistance developed by Mycobacterium tuberculosis. The high prevalence of such resistance in many parts of the world limits its use for treating multidrug-resistant (MDR) TB. The aims of this study are to characterize of mutations in rpsL, rrs, and gidB genes in MDR M....
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