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Article

Molecular characterization of multidrug-resistant Mycobacterium tuberculosis isolates from China.

Antimicrobial agents and chemotherapy - 1 Jan 2014

Zhao Li-Li, Chen Yan, Liu Hai-Can, Xia Qiang, Wu Xiao-Cui, Sun Qing, Zhao Xiu-Qin, Li Gui-Lian, Liu Zhi-Guang, Wan Kang-Lin

Abstract excerpt

To investigate the molecular characterization of multidrug-resistant tuberculosis (MDR-TB) isolates from China and the association of specific mutations conferring drug resistance with strains of different genotypes, we performed spoligotyping and sequenced nine loci (katG, inhA, the oxyR-ahpC intergenic region, rpoB, tlyA, eis, rrs, gyrA, and gyrB) for 128 MDR-TB isolates. Our results showed that 108 isolates...

Topics

Antitubercular Agents
Bacterial Proteins
Capreomycin
Genotype
Humans
Isoniazid
Kanamycin
Microbial Sensitivity Tests
Mycobacterium tuberculosis
Ofloxacin
Rifampin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tuberculosis, Multidrug-Resistant

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Identifiers

PMID: 24419342
DOI: 10.1128/AAC.01792-13
PMCID: PMC4023728

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