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Article

New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity

1 Aug 2015

Abstract excerpt

Drug hypersensitivity reactions are an important clinical problem for both health care and industry. Recent advances in genetics have identified a number of HLA alleles associated with a range of these adverse reactions predominantly affecting the skin but also other organs, such as the liver. The associations between abacavir hypersensitivity and HLA-B*57:01 and carbamazepine-induced Stevens-Johnson syndrome and...

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Share to Contact Dermatitis and Allergies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26254050
DOI: 10.1016/j.jaci.2015.06.022

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