Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-associated drug hypersensitivity and the prediction of adverse drug reactions.

Pharmacogenomics - 1 Oct 2017

Negrini Simone, Becquemont Laurent

Abstract excerpt

Adverse drug reactions are an important cause of morbidity and mortality and constitute the leading reason of drug withdrawal from the market. Besides classical reactions that are related to pharmacologic activity of the drug, some reactions are unpredictable, not dose dependent, and seem to occur in genetically predisposed individuals. The majority of this reaction is immunologically driven and they are referred...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Drug Hypersensitivity
Share to Drug-Induced Adverse Reactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug-Related Side Effects and Adverse Reactions

Share to Genetic Predisposition to Disease

Share to HLA Antigens

Share to Pharmacogenetics

Share to Urticaria and Related Conditions

Source

Identifiers

PMID: 29017379
DOI: 10.2217/pgs-2017-0090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-associated drug hypersensitivity and the prediction of adverse drug reactions.PMID 29017379Read ↗

Pharmacogenetics of hypersensitivity drug reactions.Semantic proximity Read ↗

HLA and pharmacogenetics of drug hypersensitivity.Semantic proximity Read ↗

An update on HLA alleles associated with adverse drug reactions.Semantic proximity Read ↗

Immunopharmacogenomics: Mechanisms of HLA-Associated Drug Reactions.Semantic proximity Read ↗

HLA alleles and drug hypersensitivity reactions.Semantic proximity Read ↗

Pharmacogenomics of drug-induced hypersensitivity reactions: challenges, opportunities and clinical implementation.Semantic proximity Read ↗

Drug Induced Hypersensitivity and the HLA ComplexSemantic proximity Read ↗

[Pharmacogenomics of severe drug hypersensitivity reactions--from bench to bedside].Semantic proximity Read ↗

HLA Association with Drug-Induced Adverse Reactions.Semantic proximity Read ↗

HLA and Delayed Drug-Induced Hypersensitivity.Semantic proximity Read ↗

[The associations between idiosyncratic adverse drug reactions and HLA alleles and their underlying mechanism].Semantic proximity Read ↗

Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.