Article
Progress in study on the association between HLA genetic variation and adverse drug reactions.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 28 Apr 2021
Liu Yating, Zeng Xiangchang, Ouyang Dongsheng
Abstract excerpt
The human leukocyte antigen (HLA) molecules encoded within the human major histocompatibility complex are a group of highly conserved cell surface proteins, which are related to antigen recognition. HLA genes display a high degree of genetic polymorphism, which is the basis of individual differences in immunity. Specific HLA genotypes have been highly associated with typical adverse drug reactions. HLA-A*31:01...
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