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Article

HLA alleles and drug hypersensitivity reactions.

International journal of immunogenetics - 1 Apr 2012

Profaizer T, Eckels D

Abstract excerpt

The human leucocyte antigen (HLA) system is well known for its association with certain diseases such as ankylosing spondylitis, celiac disease and many others. More recently, severe and even fatal drug hypersensitivity reactions linked to particular HLA alleles have been discovered. The significance of these discoveries has led the European Medicines Agency (EMA) and its member state agencies to recommend HLA...

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PMID: 22136512
DOI: 10.1111/j.1744-313X.2011.01061.x

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