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Article

An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity.

Journal of immunology research - 1 Jan 2018

Chen Chun-Bing, Abe Riichiro, Pan Ren-You, Wang Chuang-Wei, Hung Shuen-Iu, Tsai Yi-Giien, Chung Wen-Hung

Abstract excerpt

Drug hypersensitivity may manifest ranging from milder skin reactions (e.g., maculopapular exanthema and urticaria) to severe systemic reactions, such as anaphylaxis, drug reactions with eosinophilia and systemic symptoms (DRESS)/drug-induced hypersensitivity syndrome (DIHS), or Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). Current pharmacogenomic studies have made important strides in the...

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Identifiers

PMID: 29651444
DOI: 10.1155/2018/6431694
PMCID: PMC5830968

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