Article

Genetic associations of human leukocyte antigen alleles in cutaneous delayed drug hypersensitivity reactions: An updated review

2023-10-01

Abstract excerpt

Abstract Cutaneous delayed drug hypersensitivity reactions (DHRs) are common iatrogenic events with potentially life-threatening consequences. Delayed DHRs encompass diverse phenotypes and can be classified by their distinct T-cell responses to drug antigens. Interaction between the immune receptors, human leukocyte antigen (HLA) and T-cell receptor (TCR), and the complementary antigenic peptide is required for th...

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Literature Corpus work: 0e79ee49-891c-5a04-a2dd-b58d0f54c3ff
DOI: 10.4103/ds.ds-d-23-00082

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