Article
HLA and pharmacogenetics of drug hypersensitivity.
Pharmacogenomics - 1 Aug 2012
Pavlos Rebecca, Mallal Simon, Phillips Elizabeth
Abstract excerpt
Immunologically mediated drug reactions have been traditionally classified as unpredictable based on the fact that they cannot be predicted strictly on the pharmacological action of the drug. Such adverse drug reactions are associated with considerable morbidity and include severe cutaneous adverse reactions such as Stevens-Johnson syndrome/toxic epidermal necrolysis and the drug hypersensitivity syndromes (drug...
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