Article

Activation of CD8+ T-Cell with abacavir and HLA-B*57:01 binding peptides and elimination of T-Cell responses through chemical modification

2015-01-01

Abstract excerpt

Adverse drug reactions are responsible for 6.5% of all hospital admissions. They also affect 10 to 20% of hospitalized patients. Drug-induced hypersensitivity reactions constitute an important major subtype of type B adverse drug reactions. Low molecular weight (i.e. penicillins, sulfamethoxazole and abacavir) and high molecular weight (biologics) drugs are both associated with the inadvertent activation of the ad...

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Literature Corpus work: 7d601140-8e0c-5a78-895f-4950884fdf67
DOI: 10.17638/02028923

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