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Article

Pharmacogenomics of Drug Hypersensitivity: Technology and Translation.

Immunology and allergy clinics of North America - 1 May 2022

Kuruvilla Rebecca, Scott Kathryn, Pirmohamed Sir Munir

Abstract excerpt

Hypersensitivity reactions are caused by many structurally unrelated drugs used for many different diseases. These reactions vary in severity and can be fatal. Only a minority of patients are affected by drug hypersensitivity reactions. Predisposition seems to be mediated by genetic factors, particularly within the HLA system. Apart from HLA-B∗57:01 testing, which is routine to prevent abacavir hypersensitivity,...

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Identifiers

PMID: 35469622
DOI: 10.1016/j.iac.2022.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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