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Article

Antidepressant-like effects and basal immobility depend on age and serotonin transporter genotype.

Genes, brain, and behavior - 1 Sept 2015

Mitchell Nathan C, Koek Wouter, Daws Lynette C

Abstract excerpt

Monoamine uptake inhibitors are common treatments for depression; however, the therapeutic efficacy of these drugs varies widely. Two factors that are commonly linked to clinical outcome are age and serotonin transporter (SERT) genotype. Mouse models provide powerful tools to study consequences of age and genotype on antidepressant-like efficacy; however, to date, systematic studies of this nature are lacking....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26250357
DOI: 10.1111/gbb.12238
PMCID: PMC4710348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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