Article
Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice.
The Journal of pharmacology and experimental therapeutics - 1 Sept 2001
Mayorga A J, Dalvi A, Page M E, Zimov-Levinson S, Hen R, Lucki I
Abstract excerpt
The development of serotonin receptor knockout mice has provided an opportunity to study antidepressant drug effects in animals with targeted genetic deletion of receptors involved in antidepressant responses. In the current study, the effects of two types of antidepressant drugs, the selective serotonin reuptake inhibitors fluoxetine and paroxetine and the selective norepinephrine reuptake inhibitor desipramine,...
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