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Article

Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2002

Holmes Andrew, Yang Rebecca J, Murphy Dennis L, Crawley Jacqueline N

Abstract excerpt

Inhibition of the serotonin transporter (5-HTT) is a principal initial target of many antidepressants. However, the contribution of the 5-HTT to their therapeutic efficacy is incompletely understood. We utilized a targeted gene mutation approach to examine the role of the 5-HTT in the behavioral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12464448
DOI: 10.1016/S0893-133X(02)00374-3

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12464448-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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