Article
Strain-dependent antidepressant-like effects of citalopram in the mouse tail suspension test.
Psychopharmacology - 1 Dec 2005
Crowley James J, Blendy Julie A, Lucki Irwin
Abstract excerpt
RATIONALE: Variations in the effects of antidepressant drugs between different mouse strains are important for drug discovery and could lead to the identification of genes that predict differences in drug efficacy. OBJECTIVES: This study compared behavioral baselines and dose-dependent responses to the selective serotonin reuptake inhibitor (SSRI) citalopram in eight inbred mouse strains (C57BL/6J, DBA/2J,...
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