Article
Identification of multiple genetic loci in the mouse controlling immobility time in the tail suspension and forced swimming tests.
The Japanese journal of veterinary research - 1 May 2015
Abou-Elnaga Ahmed F, Torigoe Daisuke, Fouda Mohamed M, Darwish Ragab A, Abou-Ismail Usama A, Morimatsu Masami, Agui Takashi
Abstract excerpt
Depression is one of the most famous psychiatric disorders in humans in all over the countries and considered a complex neurobehavioral trait and difficult to identify causal genes. Tail suspension test (TST) and forced swimming test (FST) are widely used for assessing depression-like behavior and antidepressant activity in mice. A variety of antidepressant agents are known to reduce immobility time in both TST...
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