Article
Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice.
The Journal of pharmacology and experimental therapeutics - 1 Jan 2017
Mitchell Nathan C, Bowman Melodi A, Gould Georgianna G, Koek Wouter, Daws Lynette C
Abstract excerpt
Depression is a major public health concern with symptoms that are often poorly controlled by treatment with common antidepressants. This problem is compounded in juveniles and adolescents, because therapeutic options are limited to selective serotonin reuptake inhibitors (SSRIs). Moreover, therapeutic benefits of SSRIs are often especially limited in certain subpopulations of depressed patients, including...
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