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Article

Global Database-Driven Assessment of HIV-1 Adaptation to the Immune Repertoires of Human Populations.

Journal of virology - 1 Oct 2015

Karakas Aram, Brumme Zabrina L, Poon Art F Y

Abstract excerpt

Associations between HIV-1 cytotoxic T lymphocyte (CTL) escape mutations and their restricting human leukocyte antigen (HLA) alleles imply that HIV could adapt to divergent HLA repertoires of human populations globally. Using publicly available databases, we examine the relationship between the frequencies of 19 experimentally validated CTL escape mutations in HIV-1 reverse transcriptase and their restricting HLA...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to HIV Reverse Transcriptase

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Share to T-Lymphocytes, Cytotoxic

Source

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Identifiers

PMID: 26246562
DOI: 10.1128/JVI.01355-15
PMCID: PMC4580167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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