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Article

Analyzing allele specific RNA expression using mixture models.

BMC genomics - 1 Aug 2015

Lu Rong, Smith Ryan M, Seweryn Michal, Wang Danxin, Hartmann Katherine, Webb Amy, Sadee Wolfgang, Rempala Grzegorz A

Abstract excerpt

BACKGROUND: Measuring allele-specific RNA expression provides valuable insights into cis-acting genetic and epigenetic regulation of gene expression. Widespread adoption of high-throughput sequencing technologies for studying RNA expression (RNA-Seq) permits measurement of allelic RNA expression imbalance (AEI) at heterozygous single nucleotide polymorphisms (SNPs) across the entire transcriptome, and this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26231172
DOI: 10.1186/s12864-015-1749-0
PMCID: PMC4521363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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