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Article

Airpart: interpretable statistical models for analyzing allelic imbalance in single-cell datasets.

Bioinformatics (Oxford, England) - 13 May 2022

Mu Wancen, Sarkar Hirak, Srivastava Avi, Choi Kwangbom, Patro Rob, Love Michael I

Abstract excerpt

MOTIVATION: Allelic expression analysis aids in detection of cis-regulatory mechanisms of genetic variation, which produce allelic imbalance (AI) in heterozygotes. Measuring AI in bulk data lacking time or spatial resolution has the limitation that cell-type-specific (CTS), spatial- or time-dependent AI signals may be dampened or not detected. RESULTS: We introduce a statistical method airpart for identifying...

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Identifiers

PMID: 35561168
DOI: 10.1093/bioinformatics/btac212
PMCID: PMC9113279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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