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Article

ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing.

PLoS genetics - 1 May 2020

Fan Jiaxin, Hu Jian, Xue Chenyi, Zhang Hanrui, Susztak Katalin, Reilly Muredach P, Xiao Rui, Li Mingyao

Abstract excerpt

Allele-specific expression (ASE) analysis, which quantifies the relative expression of two alleles in a diploid individual, is a powerful tool for identifying cis-regulated gene expression variations that underlie phenotypic differences among individuals. Existing methods for gene-level ASE detection analyze one individual at a time, therefore failing to account for shared information across individuals. Failure...

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Identifiers

PMID: 32392242
DOI: 10.1371/journal.pgen.1008786
PMCID: PMC7241832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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