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Article

Reversion of immune escape HIV variants upon transmission: insights into effective viral immunity.

Trends in microbiology - 1 Jun 2005

Kent Stephen J, Fernandez Caroline S, Dale C Jane, Davenport Miles P

Abstract excerpt

Many viruses that cause chronic viremic infections, such as human immunodeficiency virus type 1 (HIV-1), mutate extensively to avoid effective control by the host immune system. However, each immune escape mutation probably results in some fitness cost to the virus. The most effective immune responses might be those that target the regions of the virus where escape mutation inflicts the largest fitness cost to...

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Identifiers

PMID: 15936652
DOI: 10.1016/j.tim.2005.03.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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