Article
Broad CTL Response in Early HIV Infection Drives Multiple Concurrent CTL Escapes.
PLoS computational biology - 1 Oct 2015
Leviyang Sivan, Ganusov Vitaly V
Abstract excerpt
Recent studies have highlighted the ability of HIV to escape from cytotoxic T lymphocyte (CTL) responses that concurrently target multiple viral epitopes. Yet, the viral dynamics involved in such escape are incompletely understood. Previous analyses have made several strong assumptions regarding HIV escape from CTL responses such as independent or non-concurrent escape from individual CTL responses. Using...
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