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Article

Rates of HIV immune escape and reversion: implications for vaccination.

Trends in microbiology - 1 Dec 2008

Davenport Miles P, Loh Liyen, Petravic Janka, Kent Stephen J

Abstract excerpt

HIV-1 mutates extensively in vivo to escape immune control by CD8+ T cells (CTLs). The CTL escape mutant virus might also revert back to wild-type upon transmission to new hosts if significant fitness costs are incurred by the mutation. Immune escape and reversion can be extremely fast if they oc...

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Source

Identifiers

PMID: 18964018
DOI: 10.1016/j.tim.2008.09.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18964018-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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