Article
Two transcription pause elements underlie a σ70-dependent pause cycle.
Proceedings of the National Academy of Sciences of the United States of America - 11 Aug 2015
Strobel Eric J, Roberts Jeffrey W
Abstract excerpt
The movement of RNA polymerase (RNAP) during transcription elongation is modulated by DNA-encoded elements that cause the elongation complex to pause. One of the best-characterized pause sequences is a binding site for the σ(70) initiation factor that induces pausing at a site near lambdoid phage late-gene promoters. An essential component of this σ(70)-dependent pause is the elemental pause site (EPS), a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
